Publications

• Accumulated mtDNA Mutations are Linked to Specific Impairments in NADH-Linked Respiration.
  • Franczak E, Montgomery M, Terwilliger Z, Aruleba R, Boykov I, Hagen J, Pacheco E, Chrest B, Zeczycki T, Vandiver K, Neufer D, McClung J, Fisher-Wellman K.
  • iScience, Vol 29, Issue 4, 2026
  • DOI: 10.1016/j.isci.2026.115184
• Precision Control of Nanoparticle Delivery with Engineered Biomimetic Protein Coronas.
  • Shaikh T, Amarasekara D, Hulugalla K, Toragall V, Garrigues R, Mayatt R, Werfel T, Zeczycki T, Fitzkee N.
  • ACS Nano Medicine, 2026
  • DOI: 10.1021/acsnanomed.5c00203
• Maternal Exercise Alters Placental Proteome in an Exercise Mode-Specific Manner.
  • Jevtovic F, Wisseman B, Jahan F, Claiborne A, Collier D, DeVente J, Mouro S, Zeczycki T, Szumilewicz A, Adamo K, Goodyear L, May L.
  • American Journal of Physiology-Endocrinology and Metabolism, Volume 329, Issue 6, 2025
  • DOI: 10.1152/ajpendo.00052.2025
• Effects of Maternal Exercise Modes on Infant Cord Blood Proteome.
  • Jevtovic F, Wisseman B, Jahan F, Claiborne A, Collier D, DeVente J, Mouro S, Zeczycki T, Goodyear L, May L.
  • Physiological Reports, 2025
  • DOI: 10.14814/phy2.70534
• Acute Myeloid Leukemia Mitochondria Hydrolyze ATP to Support Oxidative Metabolism and Resist Chemotherapy.
  • Hagan T, Montgomery M, Aruleba R, et al.
  • Science Advances, 11, eadu5511(2025)
  • DOI: 10.1126/sciadv.adu5511
• Sulfur Starvation Induces an Fe-Replete Response and Attenuates Virulence Pathways in Pseudomonas Aeruginosa PAO1.
  • Ugochukwu, C.G., Schwartz, T.S., Zeczycki, T.N. et al. 
  • BMC Microbiology 25, 708 (2025)
  • DOI: 10.1186/s12866-025-04442-1
• Impact of Physiological Media on Acute Myeloid Leukemia Bioenergetics and Cell Proliferation.
  • Chrest, B.R., Montgomery, M.M., Aruleba, R.T. et al. 
  • Cancer Metab 13, 25 (2025).
  • DOI: 10.1186/s40170-025-00395-1
• A Distinct Co-Expressed Sulfurtransferase Extends the Physiological Role of Mercaptopropionate Dioxygenase in Pseudomonas Aeruginosa PAO1.
  • Adindu CS, Tombrello K, Martz LA, Zeczycki T, Ellis H.
  • Biochimica et Biophysica Acta (BBA) – Proteins and Proteomics, Volume 1873, Issue 1, 2025
  • PMID: 39471965
  • DOI: 10.1016/j.bbapap.2024.141059
• The Molecular Determinants of Classical Pathway Complement Inhibition by OspEF-Related Proteins of Borrelia Burgdorferi.
  • Thomas S, Schulz AM, Leong J, Zeczycki T, Garcia, B
  • Journal of Biological Chemistry, Volume 300, Issue 5, 2024
  • DOI: 10.1016/j.jbc.2024.107236
• Pan-Tissue Mitochondrial Phenotyping Reveals Lower OXPHOS Expression and Function Across Cancer Types.
  • Boykov IN, Montgomery MM, Hagen JT, Aruleba RT, McLaughlin KL, Coalson HS, Nelson MA, Pereyra AS, Ellis JM, Zeczycki TN, Vohra NA.
  • Scientific Reports. 2023 Oct 5;13(1):16742.
  • PMID: 37798427
• Oligomeric Changes Regulate Flavin Transfer in Two-Component FMN Reductases Involved in Sulfur Metabolism.
  • Aloh CH, Zeczycki TN, Ellis HR.
  • Biochemistry. 2023 Aug 31;62(18):2751-62.
  • PMID: 37651343
• RNA Methyltransferase METTL16’s Protein Domains Have Differential Functional Effects on Cell Processes.
  • Talic ES, Wooten A, Zeczycki TN, Mansfield KD.
  • Current Issues in Molecular Biology. 2023 Jun 29;45(7):5460-80.
  • PMID: 37504262
• 2-Aminoimidazole Analogs Target PhoP Altering DNA Binding Activity and Affect Outer Membrane Stability in Gram-Negative Bacteria.
  • Zeczycki TN, Milton ME, Jung D, Thompson RJ, Jaimes FE, Hondros AD, Palethorpe S, Melander C, Cavanagh J.
  • Biochemistry. 2022 Dec 1;61(24):2948-60.
  • PMID: 36454711
• Maternal Aerobic Exercise, But Not Blood Docosahexaenoic Acid and Eicosapentaenoic Acid Concentrations, During Pregnancy Influence Infant Body Composition.
  • Strom CJ, McDonald SM, Remchak MM, Kew KA, Rushing BR, Houmard JA, Tulis DA, Pawlak R, Kelley GA, Chasan-Taber L, Newton E, Isler C, DeVente J, Raper M, May LE.
  • Int J Environ Res Public Health. 2022 Jul 7;19(14):8293. doi: 10.3390/ijerph19148293.
  • PMID: 35886147 Free PMC article. Clinical Trial.
• Bioenergetic Phenotyping of DEN-Induced Hepatocellular Carcinoma Reveals a Link Between Adenylate Kinase Isoform Expression and Reduced Complex I-Supported Respiration.
  • McLaughlin KL, Nelson MAM, Coalson HS, Hagen JT, Montgomery MM, Wooten AR, Zeczycki TN, Vohra NA, Fisher-Wellman KH.
  • Front Oncol. 2022 Jun 8;12:919880. doi: 10.3389/fonc.2022.919880. eCollection 2022.
  • PMID: 35756609 Free PMC article.
• Morphine Resistance in Spinal Cord Injury-Related Neuropathic Pain in Rats is Associated with Alterations in Dopamine and Dopamine-Related Metabolomics.
  • Rodgers HM, Patton R, Yow J, Zeczycki TN, Kew K, Clemens S, Brewer KL.
  • The Journal of Pain. 2022 May 1;23(5):772-83.
  • PMID: 34856409
• The Influence of Maternal Aerobic Exercise, Blood DHA and EPA Concentrations on Maternal Lipid Profiles.
  • Strom CJ, McDonald SM, Remchak MM, Kew KA, Rushing BR, Houmard JA, Tulis DA, Pawlak R, Kelley GA, Chasan-Taber L, Newton E, Isler C, DeVente J, Raper M, May LE.
  • Int J Environ Res Public Health. 2022 Mar 16;19(6):3550. doi: 10.3390/ijerph19063550.
  • PMID: 35329235 Free PMC article. Clinical Trial.
• Reduced Vitellogenesis and Female Fertility in Gper Knockout Zebrafish.
  • Wu XJ, Williams MJ, Kew KA, Converse A, Thomas P, Zhu Y.
  • Front Endocrinol (Lausanne). 2021 Mar 9;12:637691. doi: 10.3389/fendo.2021.637691. eCollection 2021.
  • PMID: 33790865 Free PMC article.
• Proteomic Identification of Tumor- and Metastasis-Associated Galectin-1 in Claudin-Low Breast Cancer.
  • Balestrieri K, Kew K, McDaniel M, Ramez M, Pittman HK, Murray G, Vohra N, Verbanac K.
  • Biochimica et Biophysica Acta (BBA) – Volume 1865, Issue 2, 2021, ISSN 0304-4165
  • https://doi.org/10.1016/j.bbagen.2020.129784.
• Novel Approach to Quantify Mitochondrial Content and Intrinsic Bioenergetic Efficiency Across Organs.
  • McLaughlin KL, Hagen JT, Coalson HS, Nelson MAM, Kew KA, Wooten AR, Fisher-Wellman KH.
  • Sci Rep. 2020 Oct 19;10(1):17599. doi: 10.1038/s41598-020-74718-1.
  • PMID: 33077793 Free PMC article.
• Subcellular Proteomics Combined with Bioenergetic Phenotyping Reveals Protein Biomarkers of Respiratory Insufficiency in the Setting of Proofreading-Deficient Mitochondrial Polymerase.
  • McLaughlin KL, Kew KA, McClung JM, Fisher-Wellman KH.
  • Sci Rep. 2020 Feb 27;10(1):3603. doi: 10.1038/s41598-020-60536-y.
  • PMID: 32107436 Free PMC article.
• Subfertility and Reduced Progestin Synthesis in Pgrmc2 Knockout Zebrafish.
  • Wu XJ, Williams MJ, Patel PR, Kew KA, Zhu Y.
  • Gen Comp Endocrinol. 2019 Oct 1;282:113218. doi: 10.1016/j.ygcen.2019.113218. Epub 2019 Jul 10.
  • PMID: 31301284 Free PMC article.
• Anatomical-Molecular Distribution of EphrinA1 in Infarcted Mouse Heart Using MALDI Mass Spectrometry Imaging.
  • Lefcoski S, Kew K, Reece S, Torres MJ, Parks J, Reece S, de Castro Brás LE, Virag JAI.
  • J Am Soc Mass Spectrom. 2018 Mar;29(3):527-534. doi: 10.1007/s13361-017-1869-7. Epub 2018 Jan 5.
  • PMID: 29305797 Free PMC article.
• 17β-Estradiol Directly Lowers Mitochondrial Membrane Microviscosity and Improves Bioenergetic Function in Skeletal Muscle.
  • Torres MJ, Kew KA, Ryan TE, Pennington ER, Lin CT, Buddo KA, Fix AM, Smith CA, Gilliam LA, Karvinen S, Lowe DA, Spangenburg EE, Zeczycki TN, Shaikh SR, Neufer PD.
  • Cell Metab. 2018 Jan 9;27(1):167-179.e7. doi: 10.1016/j.cmet.2017.10.003. Epub 2017 Nov 2.
  • PMID: 29103922 Free PMC article.