MALDI-TOF/TOF (Bruker)

This instrument is used for assessing the mass of intact proteins/protein complexes and simple “proteomics” (peptides/protein fingerprinting in simple mixtures).

Acknowledgements

  • Installation: 2017
  • Funds: Donation from Golden Leaf Foundation
  • Funds: Workstation upgrade with Cares Act

Current Projects

  • SARS-CoV-2 protein structure
  • Protein post-translational modifications/oxidative stress
  • Routine protein/peptide molecular weight determinations

Previous Projects

  • Myocardial infarction/ephrin-a1
  • Restless leg syndrome
  • Breast cancer (triple negative biomarkers)
  • Neurodegenerative disease (synuclein, tau aggregation mechanisms)